Stronger muscle powered by the gut.
Stronger muscle
powered by the gut.
powered by the gut.
Clinically proven to increase muscle power by +14%*
The first targeted daily postbiotic to build strength by optimizing the gut-muscle connection.
Spindle Muscle+
Built for the gut-muscle connection.
Each capsule is formulated with a precise, clinically tested dose of Akkermansia MYO™ to support the gut–muscle connection, reinforcing the gut barrier, supporting a healthy inflammatory response, and helping activate the pathways your body uses to build strength.
Timeline
What happens when you take Muscle+?
Akkermansia MYO™ begins working within hours. Measurable strength gains register at week 12
Hour 4
Postbiotic absorbed
The active components of Akkermansia MYO™ reach the gut, attach to the barrier lining and begin signaling.
Day 1
The right signals received
Your muscle cells start to receive the right cellular signals that protect muscle from breakdown
Week 4
Gut barrier strengthens
The protective mucus layer thickens in the gut. In healthy adults, metabolic inflammation calms, and blood sugar control improves.
Week 12
Measurable strength gains
The body burns energy more efficiently, skeletal muscle mass increases, and body fat can decline. In clinical trials, results show measurable improvement in lower leg strength and grip strength.
Beyond Week 12
Sustained benefits
With ongoing daily consumption and healthy habits, metabolic, gut, and muscle benefits can be sustained. Your muscles evolve to a more resilient set point — supporting healthy aging over time.
Statements describing biological mechanisms between Hour 4- Week 4 are based on in vitro (cell culture) and in vivo (animal) studies. These describe what the science shows is happening at the cellular and tissue level and are not clinical claims of effects experienced by consumers at these timepoints. Week 12 outcomes were observed results from clinical trials.1,2 Individual results may vary. Statements regarding benefits beyond 12 weeks reflect continued daily use. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare provider before use if you are pregnant, breastfeeding, taking medication, or have a medical condition.
Get more of what matters for healthy aging
SUBSTANTIATED CLAIMS |
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Live Akkermansia |
Lactobacillus (probiotic) |
Urolithin A |
BCAA (Amino Acids) |
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Clinically proven to increase muscle strength | |||||
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Supports muscle performance & power | |||||
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Helps preserve lean muscle | |||||
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Targets metabolic health at the gut level | |||||
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Supports healthier body composition in overweight individuals | |||||
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Supports gut barrier integrity | |||||
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Designed for consistent potency and shelf stability |
REFERENCES
1. Kang et al., Nutrients, 2024. Based on a randomized, placebo-controlled 12-week study of Akkermansia MYO™ in adults ages 60+ (mostly women). Mechanism of action and basic science support broader expected benefits. Individual results may vary based on biology, lifestyle, and other individual factors.
2. Third-party clinical study, data on file. Based on a randomized, placebo-controlled 12-week study of Akkermansia MYO™ in adults ages 60-80 (mostly women). Mechanism of action and basic science support broader expected benefits. Individual results may vary based on biology, lifestyle, and other individual factors.
3. Depommier et al., Nature Medicine, 2019. Based on a 3-month clinical study of pasteurized Akkermansia in overweight or obese adults with insulin resistance and metabolic syndrome. Individual results may vary.